Cushing’s syndrome

Cushing’s syndrome

Cushing’s syndrome is a hormone disorder caused by high levels of cortisol in the blood. This can be caused by taking glucocorticoid drugs, or by tumours that produce cortisol. Cushing’s disease refers to one specific cause of the syndrome: a tumour in the pituitary gland that elevates cortisol.The most common cause of Cushing’s syndrome is exogenous administration of glucocorticoids prescribed by a health care practitioner to treat other diseases. This can be an effect of steroid treatment of a variety of disorders such as asthma and rheumatoid arthritis, or in immunosuppression after an organ transplant.Symptoms include rapid weight gain, particularly of the trunk and face with sparing of the limbs. Patients are effectively treated by carefully tapering off  and  stopping the medication that causes the symptoms.


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